蓝海人类学在线 Ryan WEI's Forum of Anthropology

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楼主: Yungsiyebu

关于秘鲁罕见Q-M120 HG01944

 楼主| 发表于 2015-4-7 16:00 | 显示全部楼层
发表于 2015-4-7 21:39 | 显示全部楼层
风虎云龙 发表于 2015-4-7 11:05
发表于 2015-4-7 21:44 | 显示全部楼层
hercules 发表于 2015-4-7 21:39
发表于 2015-4-7 22:03 | 显示全部楼层
Insights into the origin of rare haplogroup C3* Y chromosomes in South America from high-density autosomal SNP genotyping


snelheid 发表于 2015-4-7 09:22
发表于 2015-4-8 02:20 | 显示全部楼层
文章很有趣,不过我觉得这类文章都有模型简单的毛病。比如人类最初进入美洲就有至少两批不同的人群,一群接近日本Ainu,一群现代美洲人。我猜C3*就是前一批,由于来得早,结果被裹挟在迁徙的最前线一直到南美洲。也就 ...
hercules 发表于 2015-4-7 22:03


而且该文最关键的问题是没法进行纯Y层面的全序测试,所以最后不得不resort to常染SNP分型,而这无异于缘木求鱼且大大增加了推测难度

In this follow-up study, we set out to revisit the three hypotheses for the origin of the C3* Y chromosomes in Ecuador. One possibility would be to sequence the Ecuadorian C3* Y chromosomes, and compare them with existing or additional East Asian C3* chromosome sequences, to determine the divergence time. However, the limited quantity and quality of DNA available did not allow this. We therefore followed another possibility, using genome-wide autosomal SNP genotyping.


Y-chromosomal variation in native South Americans: bright dots on a gray canvas.
M. Nothnagel et al.

While human populations in Europe and Asia have often been reported to reveal a concordance between their extant genetic structure and the prevailing regional pattern of geography and language, such evidence is lacking for native South Americans. In the largest study of South American natives to date, we examined the relationship between Y-chromosomal genotype on the one hand, and male geographic origin and linguistic affiliation on the other. We observed virtually no structure for the extant Y-chromosomal genetic variation of South American males that could sensibly be related to their inter-tribal geographic and linguistic relationships, augmented by locally confined Y-STR autocorrelation. Analysis of repeatedly taken random subsamples from Europe adhering to the same sampling scheme excluded the possibility that this finding was due to our specific scheme. Furthermore, for the first time, we identified a distinct geographical cluster of Y-SNP lineages C-M217 (C3*) in South America, which are virtually absent from North and Central America, but occur at high frequency in Asia. Our data suggest a late introduction of C3* into South America no more than 6,000 years ago and low levels of migration between the ancestor populations of C3* carrier and non-carriers. Our findings are consistent with a rapid peopling of the continent, followed by long periods of isolation in small groups, and highlight the fact that a pronounced correlation between genetic and geographic/cultural structure can only be expected under very specific conditions.
发表于 2017-10-12 23:45 | 显示全部楼层
snelheid 发表于 2015-4-7 09:36

发表于 2017-10-13 08:58 | 显示全部楼层
兰海版主曾经说过,在南美土著人中还发现过 C1-V20

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